Wetland ponds in the Prairie Pothole Region experience significant seasonal fluctuations in water levels. They fill primarily via snowmelt and gradually dry over the open-water season, a process that is accelerating due to changing climate. This study measured mercury fluxes from a prairie wetland pond throughout the drying period to investigate the environmental factors influencing mercury emission rates. Mercury fluxes were actively measured throughout the drying period using dynamic flux chambers and a Tekran 2537A analyzer. By characterizing how mercury emissions changed as wetlands dried and identifying the factors affecting flux rates, this work improves understanding of mercury release from prairie wetlands and provides insight into the potential environmental and human health implications of climate change driven wetland drying.