As the transitional boundary between Earth’s surface and the convecting mantle, the continental lithosphere records and governs some of the most dynamic and long-lived tectonic processes on Earth, and understanding its structure and evolution remains a major geoscientific challenge. Recent advances in integrated geophysical imaging, joint inversion, and thermochemical modeling are revealing the complex architecture and history of the lithosphere at increasingly high resolution. We invite contributions that explore lithosphere structure and dynamics across spatial scales (local to regional) and from the surface into the mantle. Topics may include rifting and breakup, collision and orogenesis, craton stabilization or destruction, and surface–deep interactions such as the origin and temporal evolution of isostatic and dynamic topography and their links to tectonics and mantle flow. We particularly encourage multidisciplinary and multiphysics approaches, case studies from Canada and worldwide, and contributions from Early Career Researchers.