As innovative forms of cartography converge with environmental and social justice as part of collective and participatory mapping, an evolving approach is needed for representation of Indigenous worldviews in digital technologies. The Cree-led Tawich Indigenous knowledge study was a collective cartography project as part of the implementation plan for the Omeshkego National Marine Conservation Area (NMCA). If enacted, the NMCA would return Indigenous control of those lands and resources. A culturally relevant free and open-source GIS-style socio-technical system is now being co-developed for multiple relational spheres of Cree knowledge collected in the Tawich study, enabling data from community monitoring and research streams to inform practical applications of land stewardship. Moreover, this system is driven by Cree stories of place and space in Elder’s voices and artfully composed wildlife videos as reverence for the more-than-human world—Indigenous political advocacy is interwoven with Indigenous representation. In such digital spaces, Indigenous semantics-based architecture can reform and decolonize the technologies themselves. Underpinning the relational architecture of this project is a semantics-based graph database, a structure that is uniquely suited to make holistic, or Systemic Literacy, knowledges explicit. A graph structure details complex linkages within systems beyond “mechanical” aspects to include political, philosophical, psychological, emotional, existential, relational, and epistemological, as well as moral dimensions. As non-Indigenous researchers, our approach to constellate to holistic Indigenous systems thinking is a Cybernetics systems thinking approach, using graph structures to co-develop cartographic socio-technological systems. Working with communities that experience disproportionate effects of climate change and environmental injustice challenges can often offer radically different perspectives—when people’s relationship to the land is about more than an essential part of their survival, but as intrinsic to their identities, uplifting these narratives offer a shift in worldviews that can accommodate a new set point and flourishing innovation to meet collective challenges.